PhD Research Fellow in Soft Matter and
1 day ago
Position as PhD Research Fellow in Controlling Molecular Transport and Cargo Delivery across Lipid Membranes available at the Department of Chemistry.
No one can be appointed for more than one PhD Research Fellowship period at the University of Oslo.
The fellowship period is 3 years. A fourth year may be considered with a workload of 25 % that may consist of teaching, supervision duties, and/or research assistance, depending upon the qualification of the applicant and the current needs of the department.
This is a PhD-project within the CLIMB project (ID 101169269), funded under the Marie Skłodowska-Curie Actions Doctoral Network (MSCA-DN). CLIMB is a highly interdisciplinary Doctoral Network designed to advance our understanding of lipid membrane complexity and its potential for applications in biotechnology, healthcare, and sustainability. The project focuses on studying the complex interplay between lipid composition, structural properties, and membrane-driven interactions, with the aim of developing advanced lipid-based materials for a variety of applications. Key research themes include:
- Understanding the role of lipid compositional complexity in membrane properties and functions.
- Developing lipid nanomaterials for use in mRNA delivery systems, bio-sensors, and sustainable formulations.
- Physicochemical characterization of aggregates formed by novel lipid mixtures, including natural extracts and polymer/peptoid coatings.
Doctoral Candidates will benefit from a rich, multidisciplinary training environment, with opportunities to collaborate with both small and large industrial partners, contributing to cutting-edge research with real-world applications. Selected candidates will engage in multidisciplinary research, participate in international secondments across academic and industrial settings, and contribute to high-impact publications and conferences.
PhD-project in Oslo
Antimicrobial resistance (AMR) is a leading global challenge of the 21st century. Antimicrobial peptides (AMPs) serve as a defence against pathogens. Their effectiveness is generally attributed to their ability to disrupt bacterial lipid membranes, leading to bacterial death. However, the molecular details of their membrane interactions remain poorly understood. This PhD project aims to explore how AMPs interact with model membranes, utilizing X-ray and neutron scattering methods, complemented by computational modelling.
The PhD candidate will undertake the design and preparation of model systems, such as lipid-based vesicles and nanoparticles. She/he will perform scattering experiments at major facilities and in home X-ray/light scattering labs, in addition to contributing to simulations and quantitative data modelling. Collaboration with other PhD students and principal investigators within the network will be important. A high degree of self-motivation and the ability to independently manage and troubleshoot tasks are crucial.
Minimum Requirements:
- Applicants must hold a master's degree or equivalent in Chemistry, Physics, Physical Chemistry, Biochemistry or similar fields, with minimum grade B (ECTS grading scale).
- Foreign completed degree (M.Sc.-level) corresponding to a minimum of four years in the Norwegian educational system.
- Excellent fluent oral and written communication skills in English are required.
- Ability to work independently as well as in a cross-disciplinary team is required.
Desired qualifications:
- A strong background within topics related to (bio)molecular self-assembly, peptide sciences, soft matter or other related topics in biophysics/biochemistry/physical chemistry.
- Experience in X-ray/neutron scattering techniques and associated data modelling.
- Experience in spectroscopic methods for biophysical assays.
- Previous experience in programming (C++, Python).
- Demonstrated interest in theory (thermodynamics, statistical mechanics etc.) and skills in programming and computational work.
Mobility requirement: The applicant must not have resided or carried out their main activity in Norway for more than 12 months in the 3 years immediately prior to their recruitment date.
The fellowship requires admission to the PhD programme at the Faculty of Mathematics and Natural Sciences. The application to the PhD programme must be submitted to the department no later than two months after taking up the position.
We are looking for highly motivated and ambitious PhD-candidates with good communication skills, problem-solving skills, and the ability to work both independently and in interdisciplinary teams.
We offer- Vibrant international academic environment
- Oslo's family-friendly surroundings with rich opportunities for culture and outdoor activities
- Membership in the Statens Pensjonskasse, which is one of Norway's best pension schemes
- Salary in position as Doctoral Research Fellow, position code 1017, in salary range NOK from 536 200 - 575 400, depending on competence and experience.
Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition.
ApplicationThe application must include:
- Cover letter - statement of motivation and research interests
- CV (summarizing education, positions and academic work)
- Copies of the original Bachelor and Master's degree diploma, transcripts of records and letters of recommendation
- Documentation of English proficiency if applicable
- List of publications and academic work that the applicant wishes to be considered by the evaluation committee
- Names and contact details of 2-3 references
Application with attachments must be submitted via our recruitment system Jobbnorge.
General informationThe best qualified candidates will be invited for interviews. Applicant lists can be published in accordance with Norwegian Freedom of Information Act § 25.
University of OsloThe University of Oslo is Norway's oldest and highest rated institution of research and education.
Questions about the positionContact: Reidar Lund, Professor, +47 228 55508
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