PhD Research Fellow in Soft Matter and
3 days ago
Employer: Universitetet i Oslo
Position Title: PhD Research Fellow in Soft Matter and (Bio)Physical Chemistry
Application Deadline: 12.03.2025
Employment Type: Engagement
About the Position:
Position as PhD Research Fellow in Controlling Molecular Transport and Cargo Delivery across Lipid Membranes available at the Department of Chemistry. No one can be appointed for more than one PhD Research Fellowship period at the University of Oslo. The fellowship period is 3 years. A fourth year may be considered with a workload of 25% that may consist of teaching, supervision duties, and/or research assistance, depending upon the qualification of the applicant and the current needs of the department.
Job Description:
This is a PhD project within the CLIMB project (ID 101169269), funded under the Marie Skłodowska-Curie Actions Doctoral Network (MSCA-DN). CLIMB is a highly interdisciplinary Doctoral Network designed to advance our understanding of lipid membrane complexity and its potential for applications in biotechnology, healthcare, and sustainability. Key research themes include:
- Understanding the role of lipid compositional complexity in membrane properties and functions.
- Developing lipid nanomaterials for use in mRNA delivery systems, bio-sensors, and sustainable formulations.
- Physicochemical characterization of aggregates formed by novel lipid mixtures, including natural extracts and polymer/peptoid coatings.
Doctoral Candidates will benefit from a rich, multidisciplinary training environment, with opportunities to collaborate with both small and large industrial partners, contributing to cutting-edge research with real-world applications. Selected candidates will engage in multidisciplinary research, participate in international secondments across academic and industrial settings, and contribute to high-impact publications and conferences.
PhD Project in Oslo:
This PhD project aims to explore how antimicrobial peptides (AMPs) interact with model membranes. The research will primarily utilize X-ray and neutron scattering methods, complemented by computational modelling. The objective is to examine structural changes in the membrane and shed light on AMP-induced dynamic processes, such as the transport of salt, lipids, and therapeutic cargo across bilayers and individual cells.
The PhD candidate will undertake the design and preparation of model systems, such as lipid-based vesicles and nanoparticles. She/he will perform scattering experiments at major facilities and in home X-ray/light scattering labs, in addition to contributing to simulations and quantitative data modelling. A high degree of self-motivation and the ability to independently manage and troubleshoot tasks are crucial.
Qualifications:
- Applicants must hold a master's degree or equivalent in Chemistry, Physics, Physical Chemistry, Biochemistry or similar fields.
- Excellent fluent oral and written communication skills in English are required.
- The ability to work independently as well as in a cross-disciplinary team is required.
Desired Qualifications:
- A strong background within topics related to (bio)molecular self-assembly, peptide sciences, soft matter or other related topics in biophysics/biochemistry/physical chemistry.
- Experience in X-ray/neutron scattering techniques and associated data modelling.
- Previous experience in programming (C++, Python).
Application:
The application must include:
- Cover letter - statement of motivation and research interests
- CV (summarizing education, positions and academic work - scientific publications)
- Copies of the original Bachelor and Master's degree diploma, transcripts of records and letters of recommendation
- Documentation of English proficiency if applicable
- Names and contact details of 2-3 references.
Application with attachments must be submitted via our recruitment system Jobbnorge, click 'Apply for the position'.
We offer:
- Vibrant international academic environment
- Oslo's family-friendly surroundings with rich opportunities for culture and outdoor activities
- Good welfare schemes.
- Career development programmes
- Salary in position as Doctoral Research Fellow, position code 1017, in salary range NOK from 536 200 - 575 400, depending on competence and experience.
The University of Oslo has a personnel policy objective of achieving a balanced gender composition and encourages applications from qualified candidates with disabilities, employment gaps or immigrant background.
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